hrp0094p2-282 | Growth and syndromes (to include Turner syndrome) | ESPE2021

Brain-derived neurotrophic factor and matrix metalloproteinases as markers of metabolic status in girls with Turner syndrome.

Błaszczyk Ewa , Gawlik Jakub , Gieburowska Joanna , Tokarska Agnieszka , Francuz Tomasz , Gawlik Aneta ,

Background: Turner syndrome (TS) predisposes to obesity and related metabolic disorders and presents a high risk of congenital heart defects. Growth hormone (GH) treatment used in TS girls also affects the parameters of carbohydrate-lipid metabolism. Thus, the search for new markers that could be early predictors of metabolic disorders seems to be justified.Objective and Method: The assessment and comparison of MMP-1, MMP-2, MMP-9 (matri...

hrp0097p2-104 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

Gender dysphoria, social transition, mental health and metabolites of cortisol among transgender and gender non-conforming youth in one of Polish hospitals.

Jakubowski Tomasz , Gawlik Aneta , Antosz Aleksandra , Chmiel-Aleksandrowicz Iga , Gawlik Jakub , Nowak Zuzanna

Introduction: In the body of available literature, the information on the relationship between the level of gender dysphoria (GD), social transition and mental health and hormone levels is scant.Methods: The data has been obtained from medical records of 120 transgender and gender non-conforming (TG/GNC) young patients of the pediatric and endocrinological ward of the Upper Silesian Center of Youth’s Health in Kato...

hrp0097p1-374 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

Metabolic health status and cortisol metabolism of adolescents with gender incongruence / gender dysphoria during process of diagnosis

Gawlik Aneta , Antosz Aleksandra , Chmiel-Aleksandrowicz Iga , Januszek-Trzciąkowska Aleksandra , Karbowska Dorota , Gawlik Jakub , Nowak Zuzanna , Jakubowski Tomasz

Introduction: Gender incongruence (GI) is a condition where a person's gender identity does not match their assigned sex at birth, and can lead to significant distress and gender dysphoria (GD). In various studies it has been associated with a predisposition to developing pathological eating behaviours, which in turn negatively influence the individual’s metabolic health. In our study we examine selected markers of metabolic condition and assess sur...

hrp0097p1-379 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

Hyperandrogenism in adolescents assigned female at birth during process of gender incongruence/ gender dysphoria diagnosis

Gawlik Aneta , Antosz Aleksandra , Chmiel-Aleksandrowicz Iga , Januszek-Trzciąkowska Aleksandra , Karbowska Dorota , Gawlik Jakub , Nowak Zuzanna , Jakubowski Tomasz

Introduction: Gender incongruence (GI) is a condition where a person's gender identity does not match their assigned sex at birth and can lead to significant distress and gender dysphoria (GD). Some studies have shown a higher prevalence of hyperandrogenism (HA) in transboys/transmen than among the cisgender female population and considered its meaning in the context the of gender identity development. Therefore, further studies confirming this observatio...